Preservative FreeIscaguard® PFA is a “preservative free additive” with a
synergistic combination of multifunctional cosmetic raw
materials with broad-spectrum antimicrobial protection.
Iscaguard® PFA may be classed as a “preservative free
system”. This system represent an alternative to
traditional cosmetic preservatives allowing
self-preserving formulations thereby reducing irritant
and sensitizing potentials.
Iscaguard® PFA is stable and active over a pH range of 4 to 8. Typical use levels for Iscaguard® PFA range from 0.5 % to 1.5 %. It is synergistic in combination with chelating agents.
Regulatory StatusIscaguard® PFA is permitted worldwide for use in both
leave-on and rinse-off personal care products.
EU – allowed without restriction (not listed on Annex VI)
USA – allowed without restriction
Japan – allowed without restrictions
Phenethyl alcohol is judged safe for use in cosmetics to 1.0 %. Based on the CIR review for phenethyl alcohol and the good toxicity assessment for caprylyl glycol Iscaguard® PFA should be safe in cosmetics up to 1.8 %
INCI name: phenethyl alcohol, caprylyl glycol
Using Iscaguard® PFA Iscaguard® PFA is particularly suitable for emulsions, oil and surfactant based formulations and may be used in aqueous formulations up to its solubility limit i.e. 0.6 %. Iscaguard® PFA can be added to formulation at temperatures up to 80 ºC, prolonged heating at elevated temperatures is not recommended.
|Caprylyl glycol||35 - 45 (%)|
|Phenethyl alcohol||55 - 65 (%)|
|Appearance||Clear colourless liquid|
|pH (0.5% in water)||4.6|
Solubility of Iscaguard® PFA (% w/w @ 25ºC)
|Pseudomonas aeruginosa||0.10 - 0.30|
|Escherichia coli||0.10 - 0.20|
|Staphylococcus aureus||0.175 – 0.2|
|Candida albicans||0.175 – 0.25|